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Dual role of an essential HtrA2/Omi protease in the human malaria parasite: Maintenance of mitochondrial homeostasis and induction of apoptosis-like cell death under cellular stress
Members of the HtrA family of serine proteases are known to play roles in mitochondrial homeostasis as well as in programmed cell death. Mitochondrial homeostasis and metabolism are crucial for the survival and propagation of the malaria parasite within the host. Here we have functionally characteri...
Autores principales: | Singh, Shweta, Datta, Gaurav, Jain, Shaifali, Thakur, Vandana, Arora, Priya, Muneer, Azhar, Asad, Mohd, Ali, Shakir, Mohmmed, Asif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645662/ https://www.ncbi.nlm.nih.gov/pubmed/36306288 http://dx.doi.org/10.1371/journal.ppat.1010932 |
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