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Parameterized syncmer schemes improve long-read mapping

MOTIVATION: Sequencing long reads presents novel challenges to mapping. One such challenge is low sequence similarity between the reads and the reference, due to high sequencing error and mutation rates. This occurs, e.g., in a cancer tumor, or due to differences between strains of viruses or bacter...

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Detalles Bibliográficos
Autores principales: Dutta, Abhinav, Pellow, David, Shamir, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645665/
https://www.ncbi.nlm.nih.gov/pubmed/36306319
http://dx.doi.org/10.1371/journal.pcbi.1010638