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Force- and cell state–dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry

Mechanosensing is an integral part of many physiological processes including stem cell differentiation, fibrosis, and cancer progression. Two major mechanosensing systems—focal adhesions and mechanosensitive ion channels—can convert mechanical features of the microenvironment into biochemical signal...

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Detalles Bibliográficos
Autores principales: Yao, Mingxi, Tijore, Ajay, Cheng, Delfine, Li, Jinyuan Vero, Hariharan, Anushya, Martinac, Boris, Tran Van Nhieu, Guy, Cox, Charles D., Sheetz, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645726/
https://www.ncbi.nlm.nih.gov/pubmed/36351022
http://dx.doi.org/10.1126/sciadv.abo1461