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Force- and cell state–dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry
Mechanosensing is an integral part of many physiological processes including stem cell differentiation, fibrosis, and cancer progression. Two major mechanosensing systems—focal adhesions and mechanosensitive ion channels—can convert mechanical features of the microenvironment into biochemical signal...
Autores principales: | Yao, Mingxi, Tijore, Ajay, Cheng, Delfine, Li, Jinyuan Vero, Hariharan, Anushya, Martinac, Boris, Tran Van Nhieu, Guy, Cox, Charles D., Sheetz, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645726/ https://www.ncbi.nlm.nih.gov/pubmed/36351022 http://dx.doi.org/10.1126/sciadv.abo1461 |
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