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Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43

Fatty acids belong to a group of compounds already acknowledged for their broad antiviral efficacy. However, little is yet known about their effect on replication of human coronaviruses. To shed light on this subject, we first screened 15 fatty acids, three lipid-soluble vitamins, and cholesterol, o...

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Detalles Bibliográficos
Autores principales: Goc, Anna, Sumera, Waldemar, Rath, Matthias, Niedzwiecki, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645759/
https://www.ncbi.nlm.nih.gov/pubmed/36352079
http://dx.doi.org/10.1038/s41598-022-23880-9