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Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43
Fatty acids belong to a group of compounds already acknowledged for their broad antiviral efficacy. However, little is yet known about their effect on replication of human coronaviruses. To shed light on this subject, we first screened 15 fatty acids, three lipid-soluble vitamins, and cholesterol, o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645759/ https://www.ncbi.nlm.nih.gov/pubmed/36352079 http://dx.doi.org/10.1038/s41598-022-23880-9 |