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CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site
Polycomb repressive complex 2 (PRC2) plays a key role in maintaining cell identity during differentiation. Methyltransferase activity of PRC2 on histone H3 lysine 27 is regulated by diverse cellular mechanisms, including posttranslational modification. Here, we report a unique phosphorylation-depend...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645763/ https://www.ncbi.nlm.nih.gov/pubmed/36351927 http://dx.doi.org/10.1038/s41467-022-34431-1 |