Human‐specific ARHGAP11B ensures human‐like basal progenitor levels in hominid cerebral organoids

The human‐specific gene ARHGAP11B has been implicated in human neocortex expansion. However, the extent of ARHGAP11B's contribution to this expansion during hominid evolution is unknown. Here we address this issue by genetic manipulation of ARHGAP11B levels and function in chimpanzee and human...

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Detalles Bibliográficos
Autores principales: Fischer, Jan, Fernández Ortuño, Eduardo, Marsoner, Fabio, Artioli, Annasara, Peters, Jula, Namba, Takashi, Eugster Oegema, Christina, Huttner, Wieland B., Ladewig, Julia, Heide, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646322/
https://www.ncbi.nlm.nih.gov/pubmed/36098218
http://dx.doi.org/10.15252/embr.202254728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646322/
https://www.ncbi.nlm.nih.gov/pubmed/36098218
http://dx.doi.org/10.15252/embr.202254728

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