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Human‐specific ARHGAP11B ensures human‐like basal progenitor levels in hominid cerebral organoids
The human‐specific gene ARHGAP11B has been implicated in human neocortex expansion. However, the extent of ARHGAP11B's contribution to this expansion during hominid evolution is unknown. Here we address this issue by genetic manipulation of ARHGAP11B levels and function in chimpanzee and human...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646322/ https://www.ncbi.nlm.nih.gov/pubmed/36098218 http://dx.doi.org/10.15252/embr.202254728 |