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Nociceptor neurons affect cancer immunosurveillance

Solid tumours are innervated by nerve fibres that arise from the autonomic and sensory peripheral nervous systems(1–5). Whether the neo-innervation of tumours by pain-initiating sensory neurons affects cancer immunosurveillance remains unclear. Here we show that melanoma cells interact with nocicept...

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Detalles Bibliográficos
Autores principales: Balood, Mohammad, Ahmadi, Maryam, Eichwald, Tuany, Ahmadi, Ali, Majdoubi, Abdelilah, Roversi, Karine, Roversi, Katiane, Lucido, Christopher T., Restaino, Anthony C., Huang, Siyi, Ji, Lexiang, Huang, Kai-Chih, Semerena, Elise, Thomas, Sini C., Trevino, Alexandro E., Merrison, Hannah, Parrin, Alexandre, Doyle, Benjamin, Vermeer, Daniel W., Spanos, William C., Williamson, Caitlin S., Seehus, Corey R., Foster, Simmie L., Dai, Hongyue, Shu, Chengyi J., Rangachari, Manu, Thibodeau, Jacques, V. Del Rincon, Sonia, Drapkin, Ronny, Rafei, Moutih, Ghasemlou, Nader, Vermeer, Paola D., Woolf, Clifford J., Talbot, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646485/
https://www.ncbi.nlm.nih.gov/pubmed/36323780
http://dx.doi.org/10.1038/s41586-022-05374-w