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Structural basis of actin filament assembly and aging

The dynamic turnover of actin filaments (F-actin) controls cellular motility in eukaryotes and is coupled to changes in the F-actin nucleotide state(1–3). It remains unclear how F-actin hydrolyses ATP and subsequently undergoes subtle conformational rearrangements that ultimately lead to filament de...

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Detalles Bibliográficos
Autores principales: Oosterheert, Wout, Klink, Björn U., Belyy, Alexander, Pospich, Sabrina, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646518/
https://www.ncbi.nlm.nih.gov/pubmed/36289337
http://dx.doi.org/10.1038/s41586-022-05241-8