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Accurate gene consensus at low nanopore coverage

BACKGROUND: Nanopore technologies allow high-throughput sequencing of long strands of DNA at the cost of a relatively large error rate. This limits its use in the reading of amplicon libraries in which there are only a few mutations per variant and therefore they are easily confused with the sequenc...

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Detalles Bibliográficos
Autores principales: Espada, Rocío, Zarevski, Nikola, Dramé-Maigné, Adèle, Rondelez, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646519/
https://www.ncbi.nlm.nih.gov/pubmed/36352541
http://dx.doi.org/10.1093/gigascience/giac102