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Accurate gene consensus at low nanopore coverage
BACKGROUND: Nanopore technologies allow high-throughput sequencing of long strands of DNA at the cost of a relatively large error rate. This limits its use in the reading of amplicon libraries in which there are only a few mutations per variant and therefore they are easily confused with the sequenc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646519/ https://www.ncbi.nlm.nih.gov/pubmed/36352541 http://dx.doi.org/10.1093/gigascience/giac102 |