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Genome-wide mapping of somatic mutation rates uncovers drivers of cancer

Identification of cancer driver mutations that confer a proliferative advantage is central to understanding cancer; however, searches have often been limited to protein-coding sequences and specific non-coding elements (for example, promoters) because of the challenge of modeling the highly variable...

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Detalles Bibliográficos
Autores principales: Sherman, Maxwell A., Yaari, Adam U., Priebe, Oliver, Dietlein, Felix, Loh, Po-Ru, Berger, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646522/
https://www.ncbi.nlm.nih.gov/pubmed/35726091
http://dx.doi.org/10.1038/s41587-022-01353-8