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Genome-wide mapping of somatic mutation rates uncovers drivers of cancer
Identification of cancer driver mutations that confer a proliferative advantage is central to understanding cancer; however, searches have often been limited to protein-coding sequences and specific non-coding elements (for example, promoters) because of the challenge of modeling the highly variable...
Autores principales: | Sherman, Maxwell A., Yaari, Adam U., Priebe, Oliver, Dietlein, Felix, Loh, Po-Ru, Berger, Bonnie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646522/ https://www.ncbi.nlm.nih.gov/pubmed/35726091 http://dx.doi.org/10.1038/s41587-022-01353-8 |
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