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Cryo-EM structure of the SEA complex

The SEA complex (SEAC) is a growth regulator that acts as a GTPase-activating protein (GAP) towards Gtr1, a Rag GTPase that relays nutrient status to the Target of Rapamycin Complex 1 (TORC1) in yeast(1). Functionally, the SEAC has been divided into two subcomplexes: SEACIT, which has GAP activity a...

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Detalles Bibliográficos
Autores principales: Tafur, Lucas, Hinterndorfer, Kerstin, Gabus, Caroline, Lamanna, Chiara, Bergmann, Ariane, Sadian, Yashar, Hamdi, Farzad, Kyrilis, Fotis L., Kastritis, Panagiotis L., Loewith, Robbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646525/
https://www.ncbi.nlm.nih.gov/pubmed/36289347
http://dx.doi.org/10.1038/s41586-022-05370-0