Investigating the causal risk factors for self-harm by integrating Mendelian randomisation within twin modelling

Previous genetically informed studies have uncovered likely causal relationships between mental health problems and self-harm but resulting causal estimates may be biased due to unmediated pleiotropy. By fitting Mendelian Randomization - Direction of Causation (MR-DoC) models that explicitly model p...

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Detalles Bibliográficos
Autores principales: Lim, Kai Xiang, Oginni, Olakunle Ayokunmi, Rimfeld, Kaili, Pingault, Jean-Baptiste, Rijsdijk, Frühling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646538/
https://www.ncbi.nlm.nih.gov/pubmed/36103101
http://dx.doi.org/10.1007/s10519-022-10114-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646538/
https://www.ncbi.nlm.nih.gov/pubmed/36103101
http://dx.doi.org/10.1007/s10519-022-10114-x

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