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Interleukin-6 Downregulates the Expression of Vascular Endothelial-Cadherin and Increases Permeability in Renal Glomerular Endothelial Cells via the Trans-Signaling Pathway

The pathogenesis of IgA nephropathy (IgAN) is still unknown, but reportedly, interleukin 6 (IL-6) is involved in this process. However, its role in damaging glomerular endothelial cells is still unclear. Therefore, in this study, to clarify the mechanism of the pathogenesis of IgAN, we investigated...

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Detalles Bibliográficos
Autores principales: Yang, Yong-Chang, Fu, Hui, Zhang, Bo, Wu, Yu-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646551/
https://www.ncbi.nlm.nih.gov/pubmed/35870042
http://dx.doi.org/10.1007/s10753-022-01711-3