Determination of potential thresholds for N-ethyl-N-nitrosourea and ethyl methanesulfonate based on a multi-endpoint genotoxicity assessment platform in rats

The main goal of the study was to investigate the genotoxic response of N-ethyl-N-nitrosourea (ENU) and ethyl methanesulfonate (EMS) at low doses in a multi-endpoint genotoxicity assessment platform in rats and to derive potential thresholds and related metrics. Male Sprague–Dawley rats were treated...

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Detalles Bibliográficos
Autores principales: Zhu, Xuejiao, Huo, Jiao, Zeng, Zhu, Liu, Yunjie, Li, Ruirui, Chen, Yiyi, Zhang, Lishi, Chen, Jinyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646607/
https://www.ncbi.nlm.nih.gov/pubmed/35793016
http://dx.doi.org/10.1007/s11356-022-21605-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646607/
https://www.ncbi.nlm.nih.gov/pubmed/35793016
http://dx.doi.org/10.1007/s11356-022-21605-z

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