Null Function of Npr1 Disturbs Immune Response in Colonic Inflammation During Early Postnatal Stage

Natriuretic peptide receptor 1 (NPR1) is conventionally known as a regulator of vascular homeostasis. Here, we generated an Npr1 knockout mouse model with CRISPR/Cas9 technology and found that homozygous mice (Npr1(−/−)) exhibited weight loss and poor survival rate during early postnatal stage. Care...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Changkun, Liu, Hongfei, Zhan, Wenxing, Chen, Liping, Wu, Andong, Yang, Lin, Chen, Shenghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646613/
https://www.ncbi.nlm.nih.gov/pubmed/35794311
http://dx.doi.org/10.1007/s10753-022-01702-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646613/
https://www.ncbi.nlm.nih.gov/pubmed/35794311
http://dx.doi.org/10.1007/s10753-022-01702-4

Ejemplares similares