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Null Function of Npr1 Disturbs Immune Response in Colonic Inflammation During Early Postnatal Stage
Natriuretic peptide receptor 1 (NPR1) is conventionally known as a regulator of vascular homeostasis. Here, we generated an Npr1 knockout mouse model with CRISPR/Cas9 technology and found that homozygous mice (Npr1(−/−)) exhibited weight loss and poor survival rate during early postnatal stage. Care...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646613/ https://www.ncbi.nlm.nih.gov/pubmed/35794311 http://dx.doi.org/10.1007/s10753-022-01702-4 |