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Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Patients with non-small cell lung cancer (NSCLC) who have distant metastases have a poor prognosis. To determine which genomic factors of the primary tumor are associated with metastasis, we analyzed data from 759 patients originally diagnosed with stage I–III NSCLC as part of the AACR Project GENIE...

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Detalles Bibliográficos
Autores principales: Van Egeren, Debra, Kohli, Khushi, Warner, Jeremy L., Bedard, Philippe L., Riely, Gregory, Lepisto, Eva, Schrag, Deborah, LeNoue-Newton, Michele, Catalano, Paul, Kehl, Kenneth L., Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646734/
https://www.ncbi.nlm.nih.gov/pubmed/36351964
http://dx.doi.org/10.1038/s41598-022-21448-1