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Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition
The type II AAA + ATPase Drg1 is a ribosome assembly factor, functioning to release Rlp24 from the pre-60S particle just exported from nucleus, and its activity in can be inhibited by a drug molecule diazaborine. However, molecular mechanisms of Drg1-mediated Rlp24 removal and diazaborine-mediated i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646744/ https://www.ncbi.nlm.nih.gov/pubmed/36351914 http://dx.doi.org/10.1038/s41467-022-34511-2 |