Mitochondrial glutamine transporter SLC1A5_var, a potential target to suppress astrocyte reactivity in Parkinson’s Disease

SLC1A5 variant (SLC1A5_var) is identified as a mitochondrial glutamine transporter in cancer cells recently. However, the role of SLC1A5_var in Parkinson’s disease (PD) is completely unknown. Here, we found the significant downregulation of SLC1A5_var in astrocytes and midbrain of mice treated with...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Cao, Lei, Song, Yuting, Kang, Zhengwei, Liu, Ting, Ding, Jianhua, Hu, Gang, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646772/
https://www.ncbi.nlm.nih.gov/pubmed/36351889
http://dx.doi.org/10.1038/s41419-022-05399-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646772/
https://www.ncbi.nlm.nih.gov/pubmed/36351889
http://dx.doi.org/10.1038/s41419-022-05399-z

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