AQbD based green UPLC method to determine mycophenolate mofetil impurities and Identification of degradation products by QToF LCMS

We report an ideal method for quantifying impurities in mycophenolate mofetil drug substances and their oral suspension preparations. We developed a systematic and eco-friendly analytical approach utilizing quality by design (QbD) and green chemistry principles. Initially, the critical method parame...

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Detalles Bibliográficos
Autores principales: Muchakayala, Siva Krishna, Katari, Naresh Kumar, Saripella, Kalyan Kumar, Schaaf, Henele, Marisetti, Vishnu Murthy, Kowtharapu, Leela Prasad, Jonnalagadda, Sreekantha Babu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646803/
https://www.ncbi.nlm.nih.gov/pubmed/36352016
http://dx.doi.org/10.1038/s41598-022-22998-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646803/
https://www.ncbi.nlm.nih.gov/pubmed/36352016
http://dx.doi.org/10.1038/s41598-022-22998-0

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