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Females exhibit higher GluA2 levels and outperform males in active place avoidance despite increased amyloid plaques in TgF344-Alzheimer’s rats

Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is most prevalent in females. While estrogen provides neuroprotection in females, sex mediated differences in the development of AD pathology are not fully elucidated. Therefore, comparing events between sexes in early-stage AD...

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Detalles Bibliográficos
Autores principales: Chaudry, Osama, Ndukwe, Kelechi, Xie, Lei, Figueiredo-Pereira, Maria, Serrano, Peter, Rockwell, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646806/
https://www.ncbi.nlm.nih.gov/pubmed/36352024
http://dx.doi.org/10.1038/s41598-022-23801-w