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Capture at the ER-mitochondrial contacts licenses IP(3) receptors to stimulate local Ca(2+) transfer and oxidative metabolism

Endoplasmic reticulum-mitochondria contacts (ERMCs) are restructured in response to changes in cell state. While this restructuring has been implicated as a cause or consequence of pathology in numerous systems, the underlying molecular dynamics are poorly understood. Here, we show means to visualiz...

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Detalles Bibliográficos
Autores principales: Katona, Máté, Bartók, Ádám, Nichtova, Zuzana, Csordás, György, Berezhnaya, Elena, Weaver, David, Ghosh, Arijita, Várnai, Péter, Yule, David I., Hajnóczky, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646835/
https://www.ncbi.nlm.nih.gov/pubmed/36351901
http://dx.doi.org/10.1038/s41467-022-34365-8