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Super-enhancers in esophageal carcinoma: Transcriptional addictions and therapeutic strategies
The tumorigenesis of esophageal carcinoma arises from transcriptional dysregulation would become exceptionally dependent on specific regulators of gene expression, which could be preferentially attributed to the larger non-coding cis-regulatory elements, i.e. super-enhancers (SEs). SEs, large genomi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647064/ https://www.ncbi.nlm.nih.gov/pubmed/36387198 http://dx.doi.org/10.3389/fonc.2022.1036648 |