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Super-enhancers in esophageal carcinoma: Transcriptional addictions and therapeutic strategies

The tumorigenesis of esophageal carcinoma arises from transcriptional dysregulation would become exceptionally dependent on specific regulators of gene expression, which could be preferentially attributed to the larger non-coding cis-regulatory elements, i.e. super-enhancers (SEs). SEs, large genomi...

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Detalles Bibliográficos
Autores principales: Shi, Yang, Wang, Meiqi, Liu, Dan, Ullah, Saif, Ma, Xing, Yang, Huiyu, Liu, Bingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647064/
https://www.ncbi.nlm.nih.gov/pubmed/36387198
http://dx.doi.org/10.3389/fonc.2022.1036648