Anakinra Pilot – a clinical trial to demonstrate safety, feasibility and pharmacokinetics of interleukin 1 receptor antagonist in preterm infants

BACKGROUND: Bronchopulmonary dysplasia (BPD), its complication pulmonary hypertension (BPD-PH) and preterm brain and gut injury lead to significant morbidity and mortality in infants born extremely prematurely. There is extensive evidence that the pro-inflammatory cytokine interleukin 1 (IL-1) plays...

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Detalles Bibliográficos
Autores principales: Green, Elys A., Metz, David, Galinsky, Robert, Atkinson, Rebecka, Skuza, Elizbeth M., Clark, Megan, Gunn, Alistair J, Kirkpatrick, Carl M., Hunt, Rod W., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647081/
https://www.ncbi.nlm.nih.gov/pubmed/36389766
http://dx.doi.org/10.3389/fimmu.2022.1022104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647081/
https://www.ncbi.nlm.nih.gov/pubmed/36389766
http://dx.doi.org/10.3389/fimmu.2022.1022104

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