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Combined unsupervised and semi-automated supervised analysis of flow cytometry data reveals cellular fingerprint associated with newly diagnosed pediatric type 1 diabetes

An unbiased and replicable profiling of type 1 diabetes (T1D)-specific circulating immunome at disease onset has yet to be identified due to experimental and patient selection limitations. Multicolor flow cytometry was performed on whole blood from a pediatric cohort of 107 patients with new-onset T...

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Detalles Bibliográficos
Autores principales: Bechi Genzano, Camillo, Bezzecchi, Eugenia, Carnovale, Debora, Mandelli, Alessandra, Morotti, Elisa, Castorani, Valeria, Favalli, Valeria, Stabilini, Angela, Insalaco, Vittoria, Ragogna, Francesca, Codazzi, Valentina, Scotti, Giulia Maria, Del Rosso, Stefania, Mazzi, Benedetta Allegra, De Pellegrin, Maurizio, Giustina, Andrea, Piemonti, Lorenzo, Bosi, Emanuele, Battaglia, Manuela, Morelli, Marco J., Bonfanti, Riccardo, Petrelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647173/
https://www.ncbi.nlm.nih.gov/pubmed/36389771
http://dx.doi.org/10.3389/fimmu.2022.1026416