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A study of the heat-mediated phase transformations of praziquantel hydrates. Evaluation of their impact on the dissolution rate
Comprehensive knowledge of the critical properties of the active pharmaceutical ingredients is a requirement within the modern concept of quality. Praziquantel hemihydrate (HH) and monohydrate (MH) are new solid forms of this antihelmintic agent, which have better solubility properties than the comm...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647200/ https://www.ncbi.nlm.nih.gov/pubmed/36387505 http://dx.doi.org/10.1016/j.heliyon.2022.e11317 |