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A study of the heat-mediated phase transformations of praziquantel hydrates. Evaluation of their impact on the dissolution rate
Comprehensive knowledge of the critical properties of the active pharmaceutical ingredients is a requirement within the modern concept of quality. Praziquantel hemihydrate (HH) and monohydrate (MH) are new solid forms of this antihelmintic agent, which have better solubility properties than the comm...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647200/ https://www.ncbi.nlm.nih.gov/pubmed/36387505 http://dx.doi.org/10.1016/j.heliyon.2022.e11317 |