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In vivo screening of subcutaneous tolerability for the development of novel excipients

To develop safe subcutaneous formulations and minimize the risk of local irritation, it is essential to optimize the composition of active pharmaceutical ingredients and excipients. Depending on the physicochemical properties of the active pharmaceutical ingredient, additional excipients may be requ...

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Detalles Bibliográficos
Autores principales: Takai, Yuichi, Powlin, Stephanie, Awasaki, Yasuyuki, Yamauchi, Toshiaki, Sano, Tomoya, Takahashi, Haruyuki, Ranneh, Abdul-Hackam, Arai, Yuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647210/
https://www.ncbi.nlm.nih.gov/pubmed/36406168
http://dx.doi.org/10.1293/tox.2022-0035