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In vivo screening of subcutaneous tolerability for the development of novel excipients
To develop safe subcutaneous formulations and minimize the risk of local irritation, it is essential to optimize the composition of active pharmaceutical ingredients and excipients. Depending on the physicochemical properties of the active pharmaceutical ingredient, additional excipients may be requ...
Autores principales: | Takai, Yuichi, Powlin, Stephanie, Awasaki, Yasuyuki, Yamauchi, Toshiaki, Sano, Tomoya, Takahashi, Haruyuki, Ranneh, Abdul-Hackam, Arai, Yuta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647210/ https://www.ncbi.nlm.nih.gov/pubmed/36406168 http://dx.doi.org/10.1293/tox.2022-0035 |
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