Changes in 5-Fluorouracil-induced external granular cell damage during the time-course of the developing cerebellum of infant rats

5-Fluorouracil (5-FU) is widely used as a chemotherapeutic agent that blocks DNA synthesis and replication by inhibiting thymidylate synthetase. This study aimed to elucidate 5-FU-induced changes in the external granular cells (EGCs) in the cerebellum of infant rats and the possible underlying mecha...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yuko, Saito, Tsubasa, Takagi, Mizuho, Nakazawa, Tomomi, Tamura, Kazutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647215/
https://www.ncbi.nlm.nih.gov/pubmed/36406170
http://dx.doi.org/10.1293/tox.2022-0003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647215/
https://www.ncbi.nlm.nih.gov/pubmed/36406170
http://dx.doi.org/10.1293/tox.2022-0003

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