Chemical-induced lung tumor in Tg-rasH2 mice: a novel mouse tumor model to assess immune checkpoint inhibitors combined with a chemotherapy drug

In subcutaneous tumor models, changes in the tumor microenvironment can lead to differences in therapeutic treatment responses between the subcutaneous and parent tumors. Accordingly, we generated a lung carcinogenesis model that combines genetically modified mice (Tg-rasH2 mice) with two-stage chem...

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Detalles Bibliográficos
Autores principales: Hagiwara, Teruaki, Numano, Takamasa, Hara, Tomomi, Sugiyama, Taiki, Mera, Yukinori, Tamano, Seiko, Miyata, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647217/
https://www.ncbi.nlm.nih.gov/pubmed/36406167
http://dx.doi.org/10.1293/tox.2022-0040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647217/
https://www.ncbi.nlm.nih.gov/pubmed/36406167
http://dx.doi.org/10.1293/tox.2022-0040

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