Cargando…

Demystifying extrachromosomal DNA circles: Categories, biogenesis, and cancer therapeutics

Since the advent of sequencing technologies in the 1990s, researchers have focused on the association between aberrations in chromosomal DNA and disease. However, not all forms of the DNA are linear and chromosomal. Extrachromosomal circular DNAs (eccDNAs) are double-stranded, closed-circled DNA con...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Manrong, Rai, Kunal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647416/
https://www.ncbi.nlm.nih.gov/pubmed/36382182
http://dx.doi.org/10.1016/j.csbj.2022.10.033