MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with BRD4/HATs inhibitors

Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have been extensively studied as biomarkers in cancer and haematological disorders, and their expression has been correlated to...

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Detalles Bibliográficos
Autores principales: Leoncini, Pier Paolo, Vitullo, Patrizia, Reddel, Sofia, Tocco, Valeria, Paganelli, Valeria, Stocchi, Francesca, Mariggiò, Elena, Massa, Michele, Nigita, Giovanni, Veneziano, Dario, Fadda, Paolo, Scarpa, Mario, Pigazzi, Martina, Bertaina, Alice, Rota, Rossella, Pagliara, Daria, Merli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647495/
https://www.ncbi.nlm.nih.gov/pubmed/36321792
http://dx.doi.org/10.3892/or.2022.8436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647495/
https://www.ncbi.nlm.nih.gov/pubmed/36321792
http://dx.doi.org/10.3892/or.2022.8436

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