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Both ANT and ATPase are essential for mitochondrial permeability transition but not depolarization

An increase in permeability of the mitochondrial inner membrane, mitochondrial permeability transition (PT), is the central event responsible for cell death and tissue damage in conditions such as stroke and heart attack. PT is caused by the cyclosporin A (CSA)-dependent calcium-induced pore, the pe...

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Detalles Bibliográficos
Autores principales: Neginskaya, M.A., Morris, S.E., Pavlov, E.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647522/
https://www.ncbi.nlm.nih.gov/pubmed/36388971
http://dx.doi.org/10.1016/j.isci.2022.105447