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Insulin-regulated aminopeptidase contributes to setting the intensity of FcR-mediated inflammation

The function of intracellular trafficking in immune-complex triggered inflammation remains poorly understood. Here, we investigated the role of Insulin-Regulated Amino Peptidase (IRAP)-positive endosomal compartments in Fc receptor (FcR)-induced inflammation. Less severe FcγR-triggered arthritis, ac...

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Detalles Bibliográficos
Autores principales: Bratti, Manuela, Vibhushan, Shamila, Longé, Cyril, Koumantou, Despoina, Ménasché, Gaël, Benhamou, Marc, Varin-Blank, Nadine, Blank, Ulrich, Saveanu, Loredana, Ben Mkaddem, Sanae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647545/
https://www.ncbi.nlm.nih.gov/pubmed/36389775
http://dx.doi.org/10.3389/fimmu.2022.1029759