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Crosstalk between TBK1/IKKε and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury

The type I interferon (TI-IFN) pathway regulates innate immunity, inflammation, and apoptosis during infection. However, the contribution of the TI-IFN pathway or upstream signaling pathways to tubular injury in kidney disease is poorly understood. Upon observing evidence of activation of upstream r...

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Detalles Bibliográficos
Autores principales: Córdoba-David, Gina, García-Giménez, Jorge, Cardoso Castelo-Branco, Regiane, Carrasco, Susana, Cannata, Pablo, Ortiz, Alberto, Ramos, Adrián M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647636/
https://www.ncbi.nlm.nih.gov/pubmed/36386242
http://dx.doi.org/10.3389/fphar.2022.987979