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MiR-146b-5p regulates IL-23 receptor complex expression in chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) cells express the interleukin-23 receptor (IL-23R) chain, but the expression of the complementary IL-12Rβ1 chain requires cell stimulation via surface CD40 molecules (and not via the B-cell receptor [BCR]). This stimulation induces the expression of a heterodimeric...

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Detalles Bibliográficos
Autores principales: Matis, Serena, Grazia Recchia, Anna, Colombo, Monica, Cardillo, Martina, Fabbi, Marina, Todoerti, Katia, Bossio, Sabrina, Fabris, Sonia, Cancila, Valeria, Massara, Rosanna, Reverberi, Daniele, Emionite, Laura, Cilli, Michele, Cerruti, Giannamaria, Salvi, Sandra, Bet, Paola, Pigozzi, Simona, Fiocca, Roberto, Ibatici, Adalberto, Angelucci, Emanuele, Gentile, Massimo, Monti, Paola, Menichini, Paola, Fronza, Gilberto, Torricelli, Federica, Ciarrocchi, Alessia, Neri, Antonino, Fais, Franco, Tripodo, Claudio, Morabito, Fortunato, Ferrarini, Manlio, Cutrona, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647700/
https://www.ncbi.nlm.nih.gov/pubmed/35819446
http://dx.doi.org/10.1182/bloodadvances.2021005726