Preparation and Characterization of Aprepitant Solid Dispersion with HPMCAS-LF

[Image: see text] This study focused on improving the physicochemical characteristics of aprepitant with poor water solubility by preparing solid dispersion (SD). To prepare the SD with HPMCAS-LF, the solvent evaporation method was applied. Based on dissolution analysis, the dissolution rate of SD i...

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Detalles Bibliográficos
Autores principales: Liu, Jinwen, Li, Yongji, Ao, Wuliji, Xiao, Yingge, Bai, Meirong, Li, Shuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647728/
https://www.ncbi.nlm.nih.gov/pubmed/36385804
http://dx.doi.org/10.1021/acsomega.2c04021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647728/
https://www.ncbi.nlm.nih.gov/pubmed/36385804
http://dx.doi.org/10.1021/acsomega.2c04021

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