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Activation of a novel α(2A)AR-spinophilin-cofilin axis determines the effect of α(2) adrenergic drugs on fear memory reconsolidation

Posttraumatic stress disorder (PTSD) after the pandemic has emerged as a major neuropsychiatric component of post-acute COVID-19 syndrome, yet the current pharmacotherapy for PTSD is limited. The use of adrenergic drugs to treat PTSD has been suggested; however, it is hindered by conflicting clinica...

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Detalles Bibliográficos
Autores principales: Saggu, Shalini, Chen, Yunjia, Cottingham, Christopher, Rehman, Hasibur, Wang, Hongxia, Zhang, Sixue, Augelli-Szafran, Corinne, Lu, Sumin, Lambert, Nevin, Jiao, Kai, Lu, Xin-Yun, Wang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647772/
https://www.ncbi.nlm.nih.gov/pubmed/36357671
http://dx.doi.org/10.1038/s41380-022-01851-w