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Ursodeoxycholic acid inhibits epithelial-mesenchymal transition, suppressing invasiveness of bile duct cancer cells: An in vitro study

Epithelial-mesenchymal transition (EMT) features are associated with pathological severity in the progression and metastasis of various cancer types, including bile duct cancer (BDC). Our previous study demonstrated that ursodeoxycholic acid (UDCA) blocked the EGFR-MAPK signaling pathway and inhibit...

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Detalles Bibliográficos
Autores principales: Lee, Jin, Hong, Eun Mi, Kim, Jung Han, Kim, Jung Hee, Jung, Jang Han, Park, Se Woo, Koh, Dong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647786/
https://www.ncbi.nlm.nih.gov/pubmed/36420069
http://dx.doi.org/10.3892/ol.2022.13568