Cargando…

A phase 1 study of donor regulatory T-cell infusion plus low-dose interleukin-2 for steroid-refractory chronic graft-vs-host disease

Chronic graft-versus-host disease (cGVHD) remains a frequent cause of nonrelapse morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Despite recent advances, options for steroid-refractory (SR) cGVHD are limited. In previous trials of low-dose interleukin-2 (LD IL-2), t...

Descripción completa

Detalles Bibliográficos
Autores principales: Whangbo, Jennifer S., Nikiforow, Sarah, Kim, Haesook T., Wahl, Jonathan, Reynolds, Carol G., Rai, Sharmila C., Kim, Soomin, Burden, Andrew, Alho, Ana C., Lacerda, João F., Alyea, Edwin P., Cutler, Corey S., Ho, Vincent T., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Koreth, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647832/
https://www.ncbi.nlm.nih.gov/pubmed/35475885
http://dx.doi.org/10.1182/bloodadvances.2021006625