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Between Protein Fold and Nucleophile Identity: Multiscale Modeling of the TEV Protease Enzyme–Substrate Complex
[Image: see text] The cysteine protease from the tobacco etch virus (TEVp) is a well-known and widely utilized enzyme. TEVp’s chymotrypsin-like fold is generally associated with serine catalytic triads that differ in terms of a reaction mechanism from the most well-studied papain-like cysteine prote...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647873/ https://www.ncbi.nlm.nih.gov/pubmed/36385818 http://dx.doi.org/10.1021/acsomega.2c05201 |