An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

BACKGROUND: Without the availability of disease-modifying drugs, there is an unmet therapeutic need for osteoarthritic patients. During osteoarthritis, the homeostasis of articular chondrocytes is dysregulated and a phenotypical transition called hypertrophy occurs, leading to cartilage degeneration...

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Detalles Bibliográficos
Autores principales: Lesage, Raphaëlle, Ferrao Blanco, Mauricio N., Narcisi, Roberto, Welting, Tim, van Osch, Gerjo J. V. M., Geris, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648005/
https://www.ncbi.nlm.nih.gov/pubmed/36352408
http://dx.doi.org/10.1186/s12915-022-01451-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648005/
https://www.ncbi.nlm.nih.gov/pubmed/36352408
http://dx.doi.org/10.1186/s12915-022-01451-8

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