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Ornidazole suppresses CD133(+) melanoma stem cells via inhibiting hedgehog signaling pathway and inducing multiple death pathways in a mouse model

AIM: To evaluate the inhibitory effects of ornidazole on the proliferation and migration of metastatic melanoma cell line (B16F10) in vitro and its anti-cancer effects in vivo using a melanoma mouse model. METHODS: We investigated the effects of ornidazole on cell viability (Crystal Violet and MTT a...

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Detalles Bibliográficos
Autores principales: Evyapan, Gulsah, Luleyap, Umit, Kaplan, Halil Mahir, Kara, Ismail Oguz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648086/
https://www.ncbi.nlm.nih.gov/pubmed/36325671
http://dx.doi.org/10.3325/cmj.2022.63.461