Cargando…

Ornidazole suppresses CD133(+) melanoma stem cells via inhibiting hedgehog signaling pathway and inducing multiple death pathways in a mouse model

AIM: To evaluate the inhibitory effects of ornidazole on the proliferation and migration of metastatic melanoma cell line (B16F10) in vitro and its anti-cancer effects in vivo using a melanoma mouse model. METHODS: We investigated the effects of ornidazole on cell viability (Crystal Violet and MTT a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Evyapan, Gulsah, Luleyap, Umit, Kaplan, Halil Mahir, Kara, Ismail Oguz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Croatian Medical Schools 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648086/ https://www.ncbi.nlm.nih.gov/pubmed/36325671 http://dx.doi.org/10.3325/cmj.2022.63.461

Ejemplares similares

Determination of the relationship between major histocompatibility complex alleles and childhood onset obsessive-compulsive disorder
por: LÜLEYAP, Ümit, et al.
Publicado: (2021)

The effects of daylight exposure on melatonin levels, Kiss1 expression, and melanoma formation in mice
por: Pazarci, Percin, et al.
Publicado: (2020)

Effects of systemic ornidazole, systemic and local compound ornidazole and pefloxacin mesylate on experimental periodontitis in rats
por: Liu, Rui, et al.
Publicado: (2012)

miR-133-mediated regulation of the Hedgehog pathway orchestrates embryo myogenesis
por: Mok, Gi Fay, et al.
Publicado: (2018)

Fixed Drug Eruption Due to Ornidazole
por: Gupta, Ramji
Publicado: (2014)

Development of Taste Masked Oral Formulation of Ornidazole
por: Shishu,, et al.
Publicado: (2010)

Multifocal fixed drug eruption due to ornidazole
por: Demirel, Fevzi, et al.
Publicado: (2014)

Ornidazole Reduces the Progression of Endometriosis in a Rat Model
por: Qin, Xiaoduo, et al.
Publicado: (2022)

The Effects of Hedgehog Signaling Pathway on the Proliferation and Apoptosis of Melanoma Cells
por: Peng, Zhi-Peng, et al.
Publicado: (2022)

Degradation of the antibiotic ornidazole in aqueous solution by using nanoscale zero-valent iron particles: kinetics, mechanism, and degradation pathway
por: Zhang, Yanchang, et al.
Publicado: (2018)

Simultaneous Spectrophotometric Estimation of Norfloxacin and Ornidazole in Tablet Dosage Form
por: Wankhede, S. B., et al.
Publicado: (2009)

Ornidazole-induced ataxia in an Indian woman: A case report
por: Gopinath, Kango Gopal, et al.
Publicado: (2015)

Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells
por: Jeng, Kuo-Shyang, et al.
Publicado: (2013)

Effects of chronic Δ(9)-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain
por: Kaplan, Halil Mahir, et al.
Publicado: (2017)

Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo
por: O’Reilly, Kathryn E., et al.
Publicado: (2013)

Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients
por: Ravishankar, P. L., et al.
Publicado: (2017)

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations
por: Grasso, Carole, et al.
Publicado: (2016)

Role of the Hedgehog Pathway and CAXII in Controlling Melanoma Cell Migration and Invasion in Hypoxia
por: Giuntini, Gaia, et al.
Publicado: (2022)

Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway
por: Kim, Bo Ram, et al.
Publicado: (2017)

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways
por: Liang, Guanzhao, et al.
Publicado: (2017)

Optimization, Characterisation and Pharmacokinetic Studies of Mucoadhesive Oral Multiple Unit Systems of Ornidazole
por: Asane, Govind S., et al.
Publicado: (2011)

Treatment of mites folliculitis with an ornidazole-based sequential therapy: A randomized trial
por: Luo, Yang, et al.
Publicado: (2016)

Ofloxacin-ornidazole fixed-dose combination medication-induced pancreatitis with positive rechallenge
por: Bush, Nikhil, et al.
Publicado: (2020)

The Hedgehog/GLI signaling pathway activates transcription of Slug (Snail2) in melanoma cells
por: Horák, Pavel, et al.
Publicado: (2023)

The Role of the Hedgehog Pathway in Cholangiocarcinoma
por: Anichini, Giulia, et al.
Publicado: (2021)

Targeting the Hedgehog Pathway in Rhabdomyosarcoma
por: Zarzosa, Patricia, et al.
Publicado: (2023)

Oxytetracycline have the therapeutic efficiency in CD133(+) HCC population through suppression CD133 expression by decreasing of protein stability of CD133
por: Song, Yeonhwa, et al.
Publicado: (2018)

Correction: Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway
por: Kim, Bo Ram, et al.
Publicado: (2018)

Dauricine suppresses the growth of pancreatic cancer in vivo by modulating the Hedgehog signaling pathway
por: Zhang, Ying-Bo, et al.
Publicado: (2019)

Simultaneous Determination of Ofloxacin and Ornidazole in Solid Dosage Form by RP-HPLC and HPTLC Techniques
por: Puranik, Manisha, et al.
Publicado: (2010)

New Spectrophotometric Estimation of Ornidazole Tablets Employing Urea as a Hydrotropic Solubilizing Additive
por: Maheshwari, R. K., et al.
Publicado: (2010)

Development and validation of a method for simultaneous estimation of ofloxacin and ornidazole in different dissolution media
por: Patel, Dasharath M., et al.
Publicado: (2012)

The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells
por: Tusa, Ignazia, et al.
Publicado: (2021)

Activation of the Hedgehog pathway in pilocytic astrocytomas
por: Rush, Sarah Z., et al.
Publicado: (2010)

Drugging Hedgehog: signaling the pathway to translation
por: Carney, Tom J, et al.
Publicado: (2013)

Hedgehog Signaling Pathway in Ovarian Cancer
por: Szkandera, Joanna, et al.
Publicado: (2013)

The Hedgehog signalling pathway regulates autophagy
por: Jimenez-Sanchez, Maria, et al.
Publicado: (2012)

Targeting the Hedgehog Pathway in Pediatric Medulloblastoma
por: Huang, Sherri Y., et al.
Publicado: (2015)

The Hedgehog signalling pathway in bone formation
por: Yang, Jing, et al.
Publicado: (2015)

Role of Hedgehog Signaling Pathway in NASH
por: Verdelho Machado, Mariana, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_918hkias3p93e8suca39vla40m