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Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

The on-going COVID-19 pandemic has given rise to SARS-CoV-2 clades and variants with differing levels of symptoms and severity. To this end, we aim to systematically elucidate the changes in the pathogenesis as SARS-CoV-2 evolved from ancestral to the recent Omicron VOC, on their mechanisms (e.g. cy...

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Detalles Bibliográficos
Autores principales: Aw, Zhen Qin, Mok, Chee Keng, Wong, Yi Hao, Chen, Huixin, Mak, Tze Minn, Lin, Raymond T. P., Lye, David Chien, Tan, Kai Sen, Chu, Justin Jang Hann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648130/
https://www.ncbi.nlm.nih.gov/pubmed/36389747
http://dx.doi.org/10.3389/fimmu.2022.950666