Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells

Human chromosomes are pervasively transcribed, but systematic understanding of coding and long noncoding RNA (lncRNA) genome function in cell differentiation is lacking. Using CRISPR interference (CRISPRi) in human induced pluripotent stem cells, we performed dual genome-wide screens—assessing 18,90...

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Detalles Bibliográficos
Autores principales: Wu, David, Poddar, Aunoy, Ninou, Elpiniki, Hwang, Elizabeth, Cole, Mitchel A., Liu, S. John, Horlbeck, Max A., Chen, Jin, Replogle, Joseph M., Carosso, Giovanni A., Eng, Nicolas W.L., Chang, Jonghoon, Shen, Yin, Weissman, Jonathan S., Lim, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648144/
https://www.ncbi.nlm.nih.gov/pubmed/36381608
http://dx.doi.org/10.1016/j.xgen.2022.100177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648144/
https://www.ncbi.nlm.nih.gov/pubmed/36381608
http://dx.doi.org/10.1016/j.xgen.2022.100177

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